Control of Messenger RNA StabilityJoel G. Belasco, George Brawerman Elsevier Science, 1993 M04 6 - 517 páginas This is the first comprehensive review of mRNA stability and its implications for regulation of gene expression. Written by experts in the field, Control of Messenger RNA Stability serves both as a reference for specialists in regulation of mRNA stability and as a general introduction for a broader community of scientists. |
Contenido
StemLoopBinding Proteins | 24 |
5 mRNA Stabilizers | 31 |
RNA Processing and Degradation by RNase | 53 |
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Términos y frases comunes
accumulation Acids activity addition altered analysis appears bacteriophage base binding Biol c-fos c-myc cells changes Chapter Chem chloroplast cleavage codon complex containing cytoplasmic deadenylation destabilizing determined effect element encoding endonucleolytic enzyme Escherichia coli et al evidence example exonuclease extracts factor FIGURE function gene gene expression Genet growth half-life histone mRNA human identified important increase indicated inhibition inhibitors initiation interaction involved iron length levels measured mechanism messenger RNA mRNA decay mRNA degradation mRNA stability mRNA turnover mutations nuclease nucleotides observed occurs oocytes PABP pathway poly(A polyadenylation possible presence Proc processing promoter protection protein protein synthesis rapid region regulation relative removal response ribonuclease ribosome RNase RNase III role Ross segment sequence shortening showed shown similar specific stem-loop structure structure studies substrate subunit suggest tail termination tion transcript translation tubulin unstable vitro vivo yeast
Referencias a este libro
Characterization of Cis-and Trans-acting Factors Required for Nonsense ... Sean Lawrence O'Connor Vista de fragmentos - 1998 |