Micro- and Nanotechnology in Vaccine DevelopmentMariusz Skwarczynski, Istvan Toth William Andrew, 2016 M09 20 - 460 páginas This book provides a comprehensive overview of how use of micro- and nanotechnology (MNT) has allowed major new advance in vaccine development research, and the challenges that immunologists face in making further progress. MNT allows the creation of particles that exploit the inherent ability of the human immune system to recognize small particles such as viruses and toxins. In combination with minimal protective epitope design, this permits the creation of immunogenic particles that stimulate a response against the targeted pathogen. The finely tuned response of the human immune system to small particles makes it unsurprising that many of the lead adjuvants and vaccine delivery systems currently under investigation are based on nanoparticles.
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Contenido
21 | |
47 | |
Chapter Four Overview of the Immune System | 63 |
Chapter Five The Role of Antigen Presentation and Innate Immunity During Immune Induction by Particulate Antigens | 83 |
Chapter Six InflammatoryNoninflammatory Adjuvants and NanotechnologyThe Secret to Vaccine Design | 99 |
Chapter Seven Vaccine Adjuvant Nanotechnologies | 127 |
Chapter Eight
NanoparticleBased Peptide Vaccines | 149 |
Chapter Nine Microparticles and Nanoparticles for CancerTargeting Vaccines | 171 |
Chapter Fourteen Microparticles for Vaccine Delivery | 259 |
Chapter Fifteen Nasal Vaccine Delivery | 279 |
Structural Modularity in Vaccine Platform Design | 303 |
Chapter Seventeen Nano and Microtechnology in Skin Delivery of Vaccines | 327 |
Chapter Eighteen Nanopatches for Vaccine Delivery | 343 |
Formulation and Device Considerations | 357 |
Chapter Twenty Nanotoxicology and Nanovaccines | 373 |
Chapter Twenty One Regulatory Development of NanotechnologyBased Vaccines | 393 |
Chapter Ten PolymerBased Nanoparticles as Modern Vaccine Delivery Systems | 185 |
Chapter Eleven VirusLike Particles | 205 |
Chapter Twelve Liposomes as a Vaccine Delivery System | 221 |
Chapter Thirteen Nanomaterials Based on Lipids for Vaccine Development | 241 |
Chapter Twenty Two Commercial Aspects of Vaccine Development | 411 |
423 | |
Back cover
| 443 |
Otras ediciones - Ver todas
Micro- and Nanotechnology in Vaccine Development Mariusz Skwarczynski,Istvan Toth Sin vista previa disponible - 2016 |