Vitamin DDavid Feldman, J. Wesley Pike, Francis H. Glorieux Elsevier, 2005 M01 25 - 1952 páginas Vitamin D, a steroid hormone, has mainly been known for its effects on bone and osteoporosis. The current therapeutic practices expand into such markets as cancer research, pediatrics, nephrology, dermatology, immunology, and genetics. This second edition includes over 100 chapters covering everything from chemistry and metabolism to mechanisms of action, diagnosis and management, new analogs, and emerging therapies. This complete reference works is a must have resource for anyone working in endocrinology, osteology, bone biology, or cancer research. *Most comprehensive, up-to-date two-volume set on Vitamin D *New chapters on squamous cell cancer, brain cancer, thyroid cancer and many more *Further sections on emerging uses for treatments of auto-immune diseases and diabetes *Over 600 illustrations and figures available on CD |
Contenido
Front Cover | 911 |
Vitamin D | iii |
iv | |
ix | |
List of Contributors | xiii |
Preface to the 2nd Edition | xxi |
Preface to the 1st Edition | xxiii |
Abbreviations | xxv |
Section VI DIAGNOSIS AND MANAGEMENT | 911 |
Section VII DISORDERS OF THE VITAMIN D ENDOCRINE SYSTEM | 1017 |
Section VIII NEW VITAMIN D ANALOGS | 1401 |
Section IX VITAMIN D AND CANCER | 1569 |
Section X EMERGING USES | 1751 |
1845 | |
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Términos y frases comunes
1,25-dihydroxyvitamin D3 25-hydroxyvitamin Acad Sci USA acid action activity addition analogs animals associated binding Biochem Biol Chem Biophys bone Bone Miner calcium calcium absorption cells changes Chapter chromatin Clin coactivator complex concentration cultures cytoplasm decrease DeLuca HF demonstrated diet differentiation domain effects elements Endocrinol Endocrinology enzyme evidence expression factor FIGURE function gene growth hormone human identified important increase indicated induced inhibition interaction intestinal involved kidney levels ligand liver matrix mechanisms mediated membrane metabolism metabolites mice mineral molecular mouse mRNA Natl Acad Sci Nature normal nuclear receptor observed osteoblasts parathyroid pathway phosphate plasma present production promoter protein region regulation renal reported response rickets role sequence serum showed shown signaling similar specific steroid stimulation structure studies suggest tion tissue transcription transport VDRE vitamin D receptor vitamin D3 vivo